Hypermethylated genes as biomarkers of breast cancer
نویسندگان
چکیده
Hypermethylated genes are emerging as some of the most promising, practical and powerful biomarkers for breast cancer detection and perhaps even of risk assessment. We have assembled a panel of methylated gene detection markers and tested them by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) in breast cancer. Here we two pilot studies: 1) detection of cancer in DNA from spontaneous nipple discharge (SND) and 2) assessing risk, and its possible reduction in contralateral breast tissue of women undergoing treatment with aromatase inhibitors.
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اپی‌ژنتیک سرطان پستان: مقاله مروری
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ورودعنوان ژورنال:
- BMC Proceedings
دوره 3 شماره
صفحات -
تاریخ انتشار 2009